For clearing the subconscious, So Darshan Kriya is a good one to look at. It can be intense. In my experience a commitment to SDK is a 24/7 process, not just your mat time. Be prepared to look at what you have repressed.
If you mean physical purification:
Pretty much any KY kriyas will purify on multiple levels.
There is a video at the 3HO site about liver purification, which is a good place to start with physical purification. It is led by Yogi B. himself
If you have heavy metals or environmental toxins, you might try chorella or celantro as an herbal chelator. Or Liver flush (lemon and olive oil first thing in the morning - lots of variations) For heavy duty cleansing you might check out a supplement called NAC. Really powerful antioxidant and liver cleaner.
Just a few ideas be more specific and I am sure you can get specific advice
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